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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 8 of 8. This is the beginning of the thread.
Posted by hugh casey on February 6, 2000, at 19:40:35
I HAVE BEEN ON NARDIL FOR AT LEAST 12 YEARS AND ITS EFFECTIVENESS IS PROBABALY DOWN TO 50-60%. DR ADDED TRAZADONE 3 YEARS AGO AND I HAD 3 OUTSTANDING MONTHS BUT THEN FADE, FADE... DR NOW TALKING ABOUT ADDING PROVIGIL (GENERIC NAME: MODAFINIL) BUT ?? RE ANY INTERACTION. ANY SUGGESTIONS ON NARDIL + OTHER RX OR RX OTHER THAN NARDIL?TKS
Posted by Cam W. on February 6, 2000, at 22:20:48
In reply to atypical depression treatment, posted by hugh casey on February 6, 2000, at 19:40:35
>
> I HAVE BEEN ON NARDIL FOR AT LEAST 12 YEARS AND ITS EFFECTIVENESS IS PROBABALY DOWN TO 50-60%. DR ADDED TRAZADONE 3 YEARS AGO AND I HAD 3 OUTSTANDING MONTHS BUT THEN FADE, FADE... DR NOW TALKING ABOUT ADDING PROVIGIL (GENERIC NAME: MODAFINIL) BUT ?? RE ANY INTERACTION. ANY SUGGESTIONS ON NARDIL + OTHER RX OR RX OTHER THAN NARDIL?
>
> TKSHugh - Some people have responded to augmentation therapy, others have responded to some of the SSRIs and others have responded to a drug holiday, then reinstitution of the MAOI in atypical depression. Talk to your doctor about these options. Many combinations have been tried, with varying degrees of success in different people. A lot of people who frequent this room have been in the same boat as you. Listen to their successes (and failures), write them down, and take them into your doctor for discussion. Perhaps someone else's success will work for you as well. There are many more ways to treat atypical depression than there were just 5 years ago. Don't give up hope. Good luck - Cam W.
Posted by Sef on February 8, 2000, at 18:20:49
In reply to atypical depression treatment, posted by hugh casey on February 6, 2000, at 19:40:35
I am new to this web site...please define 'atypical' depression. What does that mean?
Posted by jd on February 8, 2000, at 20:44:56
In reply to Re: atypical depression treatment, posted by Sef on February 8, 2000, at 18:20:49
'Atypical depression' is a term often used to describe forms of clinical depression that don't show the "typical" combination of symptoms. The most commonly cited "atypical" features are:
weight gain or increased appetite, hypersomnia, leaden paralysis, interpersonal rejection sensitivity> I am new to this web site...please define 'atypical' depression. What does that mean?
Posted by JD on February 8, 2000, at 20:58:36
In reply to Re: atypical depression treatment, posted by jd on February 8, 2000, at 20:44:56
Sef,
Whoops...computer sent my last message off while I was playing around with a list of features! Anyhow, once again, the commonly cited features of atypical depression are:
--mood reactivity (unlike "typical" depressives, can be cheered up temporarily)
--overeating or increased appetite (rather than reverse)
--oversleeping (rather than insomnia)
--high rejection sensitivity
--so-called "leaden paralysis" (i.e., patient complains of feeling "heavy", incapable of movement or action, etc.)There has been much (controversial) speculation that atypical depression may respond best to MAOIs, though SSRIs apparently can work just as well for many patients with fewer side effects. Hope this clears things up a little--hope also that you caught my note above on naltrexone dosages if you're still considering going that route!
best,
jd> 'Atypical depression' is a term often used to describe forms of clinical depression that don't show the "typical" combination of symptoms. The most commonly cited "atypical" features are:
> weight gain or increased appetite, hypersomnia, leaden paralysis, interpersonal rejection sensitivity
>
> > I am new to this web site...please define 'atypical' depression. What does that mean?
Posted by Sef on February 8, 2000, at 21:23:54
In reply to Re: atypical depression--whoops..., posted by JD on February 8, 2000, at 20:58:36
>Thanks jd, great explanation!
Sef
Posted by hec on April 19, 2000, at 13:27:26
In reply to Re: atypical depression--whoops..., posted by Sef on February 8, 2000, at 21:23:54
AFTER 12 YEARS OF NARDIL ITS EFFECTIVENESS IS PROBABALY DOWN TO 50-60%. DR ADDED TRAZADONE FEW YRS BACK AND IT WAS WONDERFUL FOR 3/4 MONTHS BUT...ANY SUGGESTIONS ON NARDIL SUPPLEMENTS OR NARDIL ALTERNATIVES OR OTHER COMBOS? (I HAVE CLASSIC ATYPICAL DEPRESSION AND EVERY DAY IS GRUELING)
TKS
Posted by Ant-Rock on April 20, 2000, at 7:37:46
In reply to Re: atypical depression treatment, posted by hec on April 19, 2000, at 13:27:26
> AFTER 12 YEARS OF NARDIL ITS EFFECTIVENESS IS PROBABALY DOWN TO 50-60%. DR ADDED TRAZADONE FEW YRS BACK AND IT WAS WONDERFUL FOR 3/4 MONTHS BUT...ANY SUGGESTIONS ON NARDIL SUPPLEMENTS OR NARDIL ALTERNATIVES OR OTHER COMBOS? (I HAVE CLASSIC ATYPICAL DEPRESSION AND EVERY DAY IS GRUELING)
> TKSParnate is a more stimulating maoi and helps many with Atypical depression. Stimulants(like ritalin) can even be added, with the supervision of a doctor of course. Tricyclics also are used to augment maoi's. Dr. Bobs tips section can provide good info. "Every day is grueling", I can definitely relate hec.
Good luck!
Anthony
This is the end of the thread.
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