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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 6 of 6. This is the beginning of the thread.
Posted by Andre Allard on August 2, 2000, at 18:30:18
I am taking 2.5mg of zyprexa for rumination on top of zoloft. The problem is that the zyprexa carries over into the next day and I am a zombie. I take the zyprexa roughly three hours before bed.
I know that seroquel has a shorter half-life then zyprexa and I was wondering whether the sedation with the seroquel would be less because of the shorter half-life.
Does anyone have any experience with these antipsychotics?
Posted by Craig on August 3, 2000, at 2:30:58
In reply to zyprexa too sedating, what about seroquel?, posted by Andre Allard on August 2, 2000, at 18:30:18
I think you're on the right track by taking Zyprexa hours before you go to bed. Instead of 3 hours before bed, try taking it as early as you can. I take 5 mg of Zyprexa about 6-7 hours before I go to bed and no longer have any hangover problems, plus I sleep great now. If you'd told me when I first began taking Zyprexa at 2.5 mg that I'd one day be able to take 5 mg of it 7 hours before I went to bed, I wouldn't have believed you. At the beginning, I felt so drugged that I didn't want to continue taking it. I'm glad I stuck it out because it's been very helpful for me.
> I am taking 2.5mg of zyprexa for rumination on top of zoloft. The problem is that the zyprexa carries over into the next day and I am a zombie. I take the zyprexa roughly three hours before bed.
>
> I know that seroquel has a shorter half-life then zyprexa and I was wondering whether the sedation with the seroquel would be less because of the shorter half-life.
>
> Does anyone have any experience with these antipsychotics?
Posted by ChrisK on August 4, 2000, at 7:02:31
In reply to zyprexa too sedating, what about seroquel?, posted by Andre Allard on August 2, 2000, at 18:30:18
How long have you been taking the Zyprexa? I found that the sedation went away after about three weeks. I take 7.5 mg after dinner and sleep well without the hangover in the morning. It just took a little while to adjust.
Posted by Andre Allard on August 4, 2000, at 17:08:47
In reply to Re: zyprexa too sedating, what about seroquel?, posted by ChrisK on August 4, 2000, at 7:02:31
I have been taking the olanzapine for almost a week. Yesterday I decided to discontinue its use because of the weight gain problem associated with the med.
Posted by paul on August 6, 2000, at 5:24:52
In reply to Re: Chris, posted by Andre Allard on August 4, 2000, at 17:08:47
i have had ZERO problems w/seroquel-in fact most days i realize that some ancient problem has suddenly become a thing of the past. no weight gain, no hangover-i'd talk to your doc and give it a try. thanks to this med i'm experiencing the FIRST true spate of brainular pacificity that i've ever known. i dont even care if i dont sleep some nighte which still happens. this is some GOOOOOOOOD stuff.
p(c(l))
Posted by Cam W. on August 7, 2000, at 9:07:34
In reply to Re: Chris, posted by Andre Allard on August 4, 2000, at 17:08:47
> I have been taking the olanzapine for almost a week. Yesterday I decided to discontinue its use because of the weight gain problem associated with the med.
Andre - Not everyone gains weight with Zyprexa, but it is far more than the 6% that the drug company reports (if I had to guess, I'd say that about 75% do get some weight gain). Very careful management of diet and exercise can help to minimize this side effect. The weight gain does plateau after about 8 or 9 months of taking the drug. The only real problem that I have noticed is that, like the SSRIs, the better the response to Zyprexa, the more likely you are to have weight gain. The sedation side effects usually subside after about a month.
Just a note - Cam
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