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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 3 of 3. This is the beginning of the thread.
Posted by bleauberry on August 5, 2008, at 18:44:22
In STARD, what did they do with patients who were obviously getting worse on their current med trial? Were they encouraged to go the full 8 weeks, or were they terminated early and moved swiftly to the next step?
So few studies talk about the people who got worse. Lots of talk of those who did respond or didn't, but hardly any about those who got worse from a particular drug.
I've searched pubmed deeply for this info and it is scarce. Only a few studies mention it. Those that did admit that the number of people who got worse on a med is in the 5% to 15% range. It was confirmed when they returned to baseline, which was improved compared to the med, after terminating the med. But I am wondering, how did STARD approach this group of patients?
Posted by Jay_Bravest_Face on August 5, 2008, at 23:14:07
In reply to Question on the STARD Protocol, posted by bleauberry on August 5, 2008, at 18:44:22
What I dont quite understand though is why do **we** need big trials to confirm this or that? (I am not talking about a drug in development) We are walking, living laboratories ourselves. I honestly think its the doctors and pdocs who need to be informed. There are SO MANY off-label uses for many different meds, many which people who have said Ive tried everything havent *really* done so. That is meant with respect to those people, but just look at the sheer number of doctors/pdocs who are simply benzo-phobic or stimulant-phobic. The research shows that most people who truly need these meds, do not abuse them. Then we have all these books by people saying this medication is evil and all, and often ends up getting a really bad name in the community, from pdocs to law enforcement. It blows my mind that you can go the variety store, buy a pack of cigarettes with a whole list of deadly chemicals in them, waiting to be in hailed by somebody, yet my Xanax prescription can evoke sheer horror in some people. Ive used Xanax, off and on, at the same dose, 0.5 to 1mgs for 10 years! I dont pop 10 pills to see what it feels like, and I get the same amazing response from the drug as I did a decade ago, when I need to lower my anxiety attacks. Stimulants have been just as trustworthy too. Never no need to increase dose, amount, etc. Then there are many mood stabilizers, antipsychotics, hormone-related treatments, meds for other illness like Parkinsons, and I am actually going to be using an anti-cancer med for my hormone problems which cannot be treated any other way.
These are just a few of the great meds a doctor can use to augment other meds and fight mental illness further. You need a doctor, though, who understands mental illness is a life-threatening illness. Somebody not just open, but also respects you and your opinion.
And with that, you make a healthy relationship, where you both respect each others opinion.Lots of people on here dig far and deep for alternative therapies, why not do so for mainstream therapies? Like Churchill, we cant give up. Some of his famous quotes, as he suffered from major anxiety, depression and the Black Dog
-If you are going through hell, keep going.-..we shall fight on the seas and oceans, we shall fight with growing confidence and growing strength in the air, we shall defend our island, whatever the cost may be, we shall fight on the beaches, we shall fight on the landing grounds, we shall fight in the fields and in the streets, we shall fight in the hills; we shall never surrender."
OkaySermon over.lol
Peace,
Jay
Posted by Phillipa on August 6, 2008, at 0:25:42
In reply to Re: Question on the STARD Protocol » bleauberry, posted by Jay_Bravest_Face on August 5, 2008, at 23:14:07
Jay what did Churchill use anything? And you're so right about benzos for me it's over 37 years and on a lower dose than when started and that is due to thyroid know you're all sick of hearing about it but it's a fact. Was on miniscule doses of xanax .125 till it went. Ugggg. Phillipa
This is the end of the thread.
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