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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 8 of 8. This is the beginning of the thread.
Posted by Uncouth on September 9, 2011, at 11:59:31
Anyone have any experience with glycine for bipolar depression? It's used for negative symptoms of schizophrenia which I feel overlap at least with my depression and in some cases are the most troublesome like apathy anhedonia a volition. I'm starting to take 40g a day. Hoping it will give me some life, buprop, adderll, mirapex, etc. Still leaving me feeling removed and helpless and passive.
Also read at glycine is in fact sedating and can cause fatigue and calming, not sure that is what I need.
Anyone have any insight? Not too many studies out there.
It's either this, or switch it up and try nmda antagonists Instead of agonists like glycine
Posted by Phillipa on September 9, 2011, at 12:47:02
In reply to Glycine for bipolar depression / neg symptoms, posted by Uncouth on September 9, 2011, at 11:59:31
Jeroen was going to try it no idea if he did? Some stuff in archieves about it. Phillipa
Posted by Zyprexa on September 11, 2011, at 23:37:26
In reply to Glycine for bipolar depression / neg symptoms, posted by Uncouth on September 9, 2011, at 11:59:31
I took it for a year or so. It was mildly sedating and didn't do a whole lot.
Posted by uncouth on October 1, 2011, at 11:40:38
In reply to Glycine for bipolar depression / neg symptoms, posted by Uncouth on September 9, 2011, at 11:59:31
Update: I am now going to try D-Aspartic Acid / Sarcosine combination that is being marketed as a testosteorne raising powder for bodybuilders. However some on the schizophrenia.com message boards have been trying it successfully for negative symptoms associated with NMDA hypofunction in schizophrenia.
This is a bit risky considering NMDA hyperfunction is one of the mechanisms postulated to cause glutamatergic excitotoxicity in depression and bipolar disorder, but i'm going to try and and see if it can help mood and motivation at all. I think its more complicated than just increase/decrease activity.
I'll let you know how things go.
Posted by Phillipa on October 1, 2011, at 19:49:51
In reply to Re: Glycine for bipolar depression / neg symptoms, posted by uncouth on October 1, 2011, at 11:40:38
Uncouth please be careful!!!! Phillipa
Posted by Chairman_MAO on October 5, 2011, at 23:53:56
In reply to Re: Glycine for bipolar depression / neg symptoms, posted by uncouth on October 1, 2011, at 11:40:38
Tread with caution ...
Posted by uncouth on October 6, 2011, at 0:16:09
In reply to Re: Glycine for bipolar depression / neg symptoms » uncouth, posted by Chairman_MAO on October 5, 2011, at 23:53:56
I may hold off on this for a while as i'm trying some other stuff right now
Posted by SLS on October 6, 2011, at 5:43:28
In reply to Re: Glycine for bipolar depression / neg symptoms, posted by uncouth on October 6, 2011, at 0:16:09
> I may hold off on this for a while as i'm trying some other stuff right now
Logical.
Good luck.
- Scott
This is the end of the thread.
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