Psycho-Babble Alternative Thread 263063

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Choline? What's the scoop?

Posted by Zenclearer on September 24, 2003, at 20:57:44

Anyone know much about cognitive effects of choline supplementation?

Some sources say it's not readily absorbed through the brain/blood barrier for conversion etc. Others say it can be helpful to supplement.

Thanks for info!

Re: Choline? What's the scoop? » Zenclearer

Posted by Larry Hoover on September 27, 2003, at 7:41:25

In reply to Choline? What's the scoop?, posted by Zenclearer on September 24, 2003, at 20:57:44

> Anyone know much about cognitive effects of choline supplementation?
>
> Some sources say it's not readily absorbed through the brain/blood barrier for conversion etc. Others say it can be helpful to supplement.
>
> Thanks for info!

I don't know about the uptake issue, but that's probably in reference to choline bitartrate. Phosphatidylcholine is certainly well absorbed and readily crosses the blood-brain barrier. It's a membrane constituent.

There's a lot of evidence that choline has mood-stabilizing properties, and may be particular useful in rapid-cycling bipolar disorder, as an augment to lithium or valproic acid.

It can be somewhat inhibitory, so depressives may not like the effect. For me, it helps balance out the effect of the excitatory supps (e.g. B-vitamins and TMG, in my own experience).

Lar

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