Psycho-Babble Alternative Thread 411145

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Low plasma vitamin E levels in major depression

Posted by tealady on November 3, 2004, at 13:47:43

http://amedeo.com/p2.php?id=15508016&s=nut
ABSTRACT available
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15508016&dopt=Abstract

Not surprised, VitE is one of my feel good supps..maybe due to the antioxidant properties
Looks like some may need more than the recommended dietary guidelines

CONCLUSION:: These findings suggest that plasma levels of alpha-tocopherol are lower in depression, but this is not likely to be the result of inability to meet recommended dietary intake

Jan

 

Re: Low plasma vitamin E levels in major depression

Posted by linkadge on November 3, 2004, at 17:06:10

In reply to Low plasma vitamin E levels in major depression, posted by tealady on November 3, 2004, at 13:47:43

Vitamin E can slash interluken-6 levels. Interluken 6 is raised in depression, and is part of the inflamitory responce.


Linkadge

 

Re: Low plasma vitamin E levels in major depression » linkadge

Posted by raybakes on November 4, 2004, at 4:22:02

In reply to Re: Low plasma vitamin E levels in major depression, posted by linkadge on November 3, 2004, at 17:06:10

> Vitamin E can slash interluken-6 levels. Interluken 6 is raised in depression, and is part of the inflamitory responce.
>
>
> Linkadge

Thanks Linkadge, on different threads I've been worried about my interleukin 6 with regard to homocysteine, parathyroid, vitamin D and A and autoimmune problems.

Ray

 

Re: Low plasma vitamin E levels in major depression » raybakes

Posted by JLx on November 4, 2004, at 9:39:18

In reply to Re: Low plasma vitamin E levels in major depression » linkadge, posted by raybakes on November 4, 2004, at 4:22:02

> > Vitamin E can slash interluken-6 levels. Interluken 6 is raised in depression, and is part of the inflamitory responce.
> >
> >
> > Linkadge
>
> Thanks Linkadge, on different threads I've been worried about my interleukin 6 with regard to homocysteine, parathyroid, vitamin D and A and autoimmune problems.
>
> Ray

You probably already know this about niacinamide, but I just read it:

"Additionally, due to its inhibition of ADP-ribosylation, niacinamide has been shown to suppress cytokine-mediated induction of nitric oxide synthase in a number of cells, thus effecting interleukin-1-exposed chondrocytes, resulting in decreased inflammation. (15)http://www.findarticles.com/p/articles/mi_m0FDN/is_6_7/ai_96416605

JL

 

Re: Low plasma vitamin E levels in major depression » JLx

Posted by raybakes on November 4, 2004, at 13:09:18

In reply to Re: Low plasma vitamin E levels in major depression » raybakes, posted by JLx on November 4, 2004, at 9:39:18


>
> "Additionally, due to its inhibition of ADP-ribosylation, niacinamide has been shown to suppress cytokine-mediated induction of nitric oxide synthase in a number of cells, thus effecting interleukin-1-exposed chondrocytes, resulting in decreased inflammation. (15)http://www.findarticles.com/p/articles/mi_m0FDN/is_6_7/ai_96416605
>

Yes the PARP molecule appears to be involved in a lot of disease progression - another abstract claims that by inhibiting PARP, niacinamide can reduce the damaging effect of homocysteine on blood vessel walls - Thanks for the article, it was really useful!

Ray

 

Re: Low plasma vitamin E levels /fish oil

Posted by tealady on November 4, 2004, at 18:55:19

In reply to Re: Low plasma vitamin E levels in major depression » JLx, posted by raybakes on November 4, 2004, at 13:09:18

So this may be why some of us,like me, feel worse on fish oil
(link from another thread by Lar)
http://www.iherb.com/fishoil.html#Vitamin%20E

Fish oil and vitamin E go together
BELTSVILLE, MARYLAND. Fish oils are beneficial in the prevention of cancer and cardiovascular disease. They do, however, oxidize very easily and therefore add to the oxidant stress on the body. An experiment was recently carried out by the U.S. Department of Agriculture to see if an increased intake of vitamin E could counteract this detrimental effect of fish oils. Forty men aged 32. to 44 were involved. The men consumed a controlled diet for a total of 28 weeks. For the first 10 weeks they received the fish oil plus 200 mg of vitamin E (all-rac-alpha-tocopherol). The urinary excretion of peroxidation products (malondialdehyde) more than doubled when the fish oil capsules were introduced but then dropped by a factor of four when vitamin E was added. The vitamin E concentration in he red blood cells dropped very significantly when fish oil was ingested but more than recovered with the vitamin E supplement.

Last year I phoned around suppliers in Oz. Seems no fish oil is produced in Oz..all imported from O'seas by ship and not refridgerated as far as I could tell.
I'd bought 4 different brands but they all seemed a bit rancid.
In the UK I bought some and it is not as smelly..so I guess all Oz fish oil is a bit sus.
Even the stuff with VitE added..got some of that too..problem is the VitE is not added until the local capsule filler adds the imported fish oil.
I did suggest refridgeration to a couple of the better suppliers but the idea didn't go down well.

It was good to see the brown bottles sitting out in the sun in open malls at the Gold Coast last summer..would have been over 100 in the shade..the bottles were too hot to touch <g>.

I do like sardines though, and feel better after eating them..but there is only so much one can eat.

Eating fish oil for me must lower an already low VitE level and cause oxidative stress too.

I do agree about needing a higher omega3:omega6 balance..but I'm trying to achieve this by eating greens, omega3 rich eggs(or grass fed), omega3 enriched bread occasionally, dairy (hopefully grass fed), not grain fed beef..but difficult to find grass fed only these days..they use trucks now for transporting the cattle instead of droving and fatten up in yards etc so unless you can find a country butcher that slaughters their own local area...
Also a spoon of linseed meal on my brekkie sometimes and sometimes flaxseed oil on skin instead of coconut oil. Using it up this way as I heard it goes rancid too, but a least it was refridgerated in the shop, if not beforehand.

any other ideas folk?

Jan

 

Re: Low plasma vitamin E levels /fish oil » tealady

Posted by JLx on November 10, 2004, at 11:05:28

In reply to Re: Low plasma vitamin E levels /fish oil, posted by tealady on November 4, 2004, at 18:55:19

> I do agree about needing a higher omega3:omega6 balance..but I'm trying to achieve this by eating greens, omega3 rich eggs(or grass fed), omega3 enriched bread occasionally, dairy (hopefully grass fed), not grain fed beef..but difficult to find grass fed only these days..they use trucks now for transporting the cattle instead of droving and fatten up in yards etc so unless you can find a country butcher that slaughters their own local area...
> Also a spoon of linseed meal on my brekkie sometimes and sometimes flaxseed oil on skin instead of coconut oil. Using it up this way as I heard it goes rancid too, but a least it was refridgerated in the shop, if not beforehand.
>
> any other ideas folk?
>
> Jan

Can you get walnut oil there? I don't much like walnuts but I use the oil a bit in cooking. Mostly I drizzle it on cut up skin-on small potatoes which I then cook (microwave, bake or in tinfoil on the grill) with minced onion and parsley. I used to use butter but the walnut oil works just as well for this recipe.

JL

 

Re: Low plasma vitamin E levels /fish oil » JLx

Posted by tealady on November 10, 2004, at 16:12:17

In reply to Re: Low plasma vitamin E levels /fish oil » tealady, posted by JLx on November 10, 2004, at 11:05:28

No can't get walnut oil over here that I know of, and I hate the taste of walnuts by themselves too..they are nice mixed in a choccy mud cake though<g>

Actually butter should be fine as far as omega3 goes, as dairy is all grass fed..in Oz and NZ anyway, not sure about countries with a lot of snow?

Jan


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